Project on Type 2 diabetic and Hyperglycemic Pancreatic Islets

Introduction

Emma

Materials / The Data Set (description)

Caroline

Materials - Wrangling

Frederik

Methods - Median Expression Differences

• Goal: Identify genes with largest expression differences between T2D and control
• Approach:
  • Compute median expression per gene for T2D and control samples
  • Calculate absolute differences between groups per gene
• Visualization:
  • Plot 30 genes with the most different expressions
  • Bar plot and boxplots

Methods - p.values

Bolette

Results - Median

Lena

Results - p.value

Emma

Results - combined / correlation matrix

vælger 10 gener, correlation matrix

Bolette

Discussion / Conclusion

1) Difference in two methods

2) Sum up which genes are found by the analysis

3) does they support the litterature? uniprot…